@akalsas, I see that this issue of headaches while sleeping continues to disrupt your life and that you haven't found answers. To help connect you with others who experience nocturnal headaches, I moved your message to this existing discussion that @taterjoy started:
Chronic severe nocturnal hypnic headaches https://connect.mayoclinic.org/discussion/chronic-severe-nocturnal-hypnic-headaches/

Recently @taterjoy shared this encouraging update https://connect.mayoclinic.org/comment/729668/

Akalsas, Have you been diagnosed with hypnic headaches? Are you a candidate to try Indomethacin? Have you tried lithium? Flunarizine? or Topirimate? or Verapamil?

Hi akalsas! I am so sorry you are having issues and need urgent advice. I experience severe nocturnal headaches four times nightly unless I take preventative meds (Indomethacin 50mg spit dose, melatonin 30mg nightly, 3/4 cup coffee 1-2 hours prior to bedtime. They were accompanied by severe chronic nausea and weight loss. I believe my local neuro checked my cortisol levels but I don't think melatonin was "checked." My Mayo Headache specialst (neurologist) had me add melotonin to my current regimen as a "trial" and it has helped to a degree. If you are loosing sleep, please be aware that there is a condition called Sleep Psychosis that can occur if you go without sleep for many nights in a row. I have not experienced that, but I know someone who did. What are your symptoms, and what type of physician are you seeking help from? Also, do you also suffer from headaches of any type (including migraines?)? My undertreated migraines were contributing to the intensity of my night nocturnal inflammatory headaches that act like Cluster headaches but do not fit that category or the new definition of Hypnic headaches. I hope you can find relief. Please reach out to me privately if needed. If you are depressed or feeling defeated, please reach out to a mental health professional if you are able to.