It is so different for all pf us. My primary doc (a DO and very current) told me the other day that there are genetics that some people have that make us suseptable to inflamation. (We were discussing my leg veins which have closed off spontaneously.) She said that it might account for the PMR. I also have glaucoma and one eye that is losing sight so the less pred the better. So I might end up with a small amout of daily pred and that may be ok. We will have to see.