← Return to Invasive Lobular Carcinoma Pleomorphic Level 3 (Oncotype Score 34)
DiscussionInvasive Lobular Carcinoma Pleomorphic Level 3 (Oncotype Score 34)
Breast Cancer | Last Active: Jun 29 11:04am | Replies (36)Comment receiving replies
Replies to "I have a second opinion scheduled at MSKCC the day after they want to put the..."
I think there is a misunderstanding here unless you're referring to some different usage?
A node 'taking dye' indicates that it is a node where the cancer cells would most likely infiltrate the lymphatic system because the dye is injected in the vicinity of the tumor tissue to identify the lymph nodes most likely at risk. (Usually the nodes closest to the cancer cells but not always. Thus the dye is used to detect the pipeline.)
If the biopsy is negative, there were no cancer cells in that 'sentinel node.' That's good news.
The Oncotype service reps are very helpful. You might want to talk to them to find out the test algorithm dealing with lobular cancers. They have strict protocols for tissue submission so I would be surprised if the test is invalid. And they do reject tissue from tumors submitted for tests that are inapplicable for that particular tumor type or stage, etc. Or with a seemingly incorrect biopsy so are careful about the integrity of the tests' statistical universe appropriateness.
I would definitely check the tailorX trial to make sure your type of cancer was part of the research because this study is used to support the Oncotype results. You could also try another genomic test like Mammaprint and others just to get another result to see if that test would indicate chemo or not. I did that and they differed. I had Stage 1 grade 1 IDC and one test showed a high risk of recurrence and the other test showed low risk of recurrence. So I am sure you will get multiple opinions which should help bring some clarity.