pemelaz - The neuro doc at Mayo did not offer an alternative med for my PN. I had been prescribed Gabapentin by my primary but did not have good results, anger issues. Not normal for me. Doc removed me from that and tried Lyrica. Did not help and while on Lyrica, Mayo said don't take it. Could be because of my type of PN. I have no pain in feet or legs, numbness only. Axonal sensory-motor PN was the final dx I got at Mayo. It is very possible Lyrica will help with other types of neuropathy, it is something each person needs to determine for themselves. Some get relief, others not. My lower back pain unrelated to PN - so the docs say. I take only tylenol and advil as needed.