← Return to CA 27-29 numbers rising: Does anyone else have an issue like this?

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@lazomama

I had a double mastectomy on 4/28/22. Started Anastrozole shortly thereafter. It was ductal carcinoma in situ, however had a small contained metastasized area in the left breast just outside the duct. They removed all breast tissue both sides & my centinal (sp) node on the left, tested no cancer present. I just had my first CA 27.29 test done and high is 38. Mine came back at 52. I am beside myself with fear. Is this number common with the
Anastrozole treatment or this soon after surgery...?

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Replies to "I had a double mastectomy on 4/28/22. Started Anastrozole shortly thereafter. It was ductal carcinoma in..."

Welcome, @lazomama. I see you found the recent discussion about CA 27-29 tumor marker. I moved your first post here too:
- CA 27-29 numbers rising: Does anyone else have an issue like this? https://connect.mayoclinic.org/discussion/ca-27-29-consistently-high-in-the-40s/

I did this so you can connect easily with other members talking about this like @cindylb @jlms @oilermama @mom23boys @keepmoving2 @elizm @auntieoakley and many others.

A few things are important to know about cancer antigen 27.29 (CA 27.29) blood test:
- The CA 27.29 test is primarily used to monitor stage 4 metastatic breast cancer.
- CA 27.29 levels will most likely rise during the first 30–90 days of cancer treatment for some patients. This is because treatment can cause the tumor to release CA 27.29 antigens into the bloodstream. Because of this, your oncologist may wait two to three months after the start of each new treatment to get an accurate test result.
- Studies have shown that the test results don't specifically differentiate breast cancer from other causes, including noncancerous causes.
- It is rare that the CA 27.29 is ordered on its own. Additionally tests are required to confirm findings.
Read more: https://www.verywellhealth.com/cancer-antigen-2729-430607

Lazomamma, it is so tough to get this information just before the weekend. You are understandably beside yourself. The community is here for you to get you through the weekend. When are you scheduled to meet with your oncologist?
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I had the same fear and had a discussion with my oncologist just a few weeks ago.

Given the imperfect nature and unreliability of the test, we decided to discontinue the use of this test as it was causing me a lot of stress as my numbers were going up and down for no rhyme or reason.

Many things can bring on a higher number such as the diet you’re consuming, alcohol and also strenuous exercise.

My oncologist then stated that this test is best used for those who are metastatic as if the numbers continuously go up, it may be evidence that the patient is no longer in remission.

She then indicated that my bloodwork, clinical exam and overall health will determine if we need to look any further for a recurrence.

Talk to your oncologist and hopefully your fears will be relieved. ♥️