Does anyone feel just awful on prednisone? I have new PMR diagnosis, with 20 mg and the side effects of prednisone are markedly worse than the pain my shoulders, elbow and wrist/hands. I am taking antacids, but there's a tightness in my chest, or esophagus, then I feel exhausted or spacey. I ended up getting more blood work done from my GP as I am now worried about an onset of diabetes. Any input would be appreciated!!!