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Aromatase Inhibitors: Did you decide to go on them or not?
Breast Cancer | Last Active: May 12, 2023 | Replies (1190)Comment receiving replies
Hi,
I do understand if at a lower dose it blocks the estrogen that side effects would be the same.
Just really curious as to why we would put more of a drug in our system than it needs.
I would think taking excess of any drug isn’t necessary or good for us and that in itself could cause side effects.
Example:
When I have allergies I take a pill. One works. Why would I take 2 or 3.
If I have a migraine and one pill works. Why would I take 2 or 3?
I really am just trying to understand.
I may be way off with my way of thinking.
That’s why I ask these things.
Doctor don’t really want to get into details.
Just the facts ma’am (Joe Friday) Maybe some of you remember him:)
Thank you for your reply.
I do appreciate it.
Replies to "Hi, I do understand if at a lower dose it blocks the estrogen that side effects..."
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Optimal dosing means just that. It means that in order to get the optimal benefit, this is the dose.
Here is an example; my husband has multiple myeloma, a bone marrow cancer. He just started Revlomid, Ninlaro, and Dexamethasone. The optimal dose is 25mg, 4mg, 40mg. But there are reduced dosing options that are also effective in “most” cases. My friend has kidney disease and she takes a much lower dose of revlomid. It is still effective but works much slower.
Does this help you understand why one does is recommended but lower dose might be effective?