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DiscussionAromatase Inhibitors: Did you decide to go on them or not?
Breast Cancer | Last Active: May 12, 2023 | Replies (1190)Comment receiving replies
Replies to "I just popped in here before getting ready for work. I was wondering about taking these..."
My doctor okayed alternating days but I ended up doing full dose anyway. The Femara insert states that 20% of the recommended dose may be effective. The half life would indicate alternate days would be effective.
The real question is, what side effects exist that are not caused by estrogen deprivation? Because no matter what the dose is, if it effectively removes estrogen produced by the adrenals, side effects would be the same.
I know there has been a few discussions about this and most doctors seem to have been open to it. These drugs have an optimal dose but not everyone can tolerate it. The side effects that are directly caused by the lack of circulating hormones would probably remain, but drug effects might be lessened.
Are you taking one of these drugs now? Are you comfortable having this discussion with your doctor?