I was diagnosed with microscopic colitis about 7 years ago through a biopsy. Nothing seemed to help the symptoms. I went to Mayo Clinic (Phoenix) and had another series of tests and was placed on Entyvio. The microscopic colitis actually had disappeared, as my colonoscopy biopsies were now negative but I do have Crohn's Disease (I have 2 markers for Crohn's) . I have been on the Entyvio for 3 years now and it does a really good job.