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How important is taking hormone blockers after surgery for IDC?

Breast Cancer | Last Active: May 8, 2023 | Replies (91)
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@nahhey

Hello,
If you don’t mind me asking.
What is considered a low on on oncotype score?
I am 63.
I know there are different margins for 50 and up.

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Replies to "Hello, If you don’t mind me asking. What is considered a low on on oncotype score?..."
anjalima | @anjalima | Sep 11, 2022

As I have read, there are two categories.

Premenopausal 18 and under is considered low.

Post menopausal 25 and under is considered low.

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callalloo | @callalloo | Sep 11, 2022

I don't remember the cut-off between low and intermediate risk for the OncotypeDX but will try to find the report with that information. I'm not certain what you're referring to as "different margins for 50 and up" but the OncotypeDX looks at the genomics of the tumor tissue. I'm not aware that it takes age or other demographics into account. It might, but that's not my impression.

OncotypeDX results can be surprising. There is one case, I believe still on their website, of a stage 4, large tumor cancer that showed a very low risk of recurrence. And a stage 1, DCIS with a very high risk of recurrence. This is interesting to me because oncologists looking at the biopsies might assume totally different risk profiles for these tumors based on their experience. And might be inclined to underestimate the risk for the stage 1 DCIS or inadvertently undertreat it.

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