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Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?
My close friend has had Pluvecto treatment suggested to him by oncologists. It is relatively new, having been approved by the FDA in March 2022. Have any of you been given this drug? I have read it is radioactive material and patient needs to stay away 6 ft from others for at least 3 days so as not to contaminate them. He has not yet decided whether to take the treatment or not as he is feeling awful enough as is.
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The biopsy is your best bet for sure. Sounds like you have a knowledgeable team and are in good hands.
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3 Reactionshttps://kcci.com/article/iowa-man-with-advanced-prostate-cancer-finds-hope-in-new-treatment-at-des-moines-hospital/41111092
While this not a particularly helpful report on the clinical side of Lu177, it is a testimonial of one patient's experience with the treatment. I hope it is helpful for at least some who follow this discussion topic.
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1 ReactionMy friend's prostate cancer is too advanced in his body (bones, soft tissues), and he has been determined to be too weak for the pluvicto treatment by his oncology team. He is electing to do hospice as he is in terrible pain.
I thank you all for your helpful and encouraging posts on this topic I started. Hugs to all.
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1 Reaction@dedehans , I am so sorry to hear about your friend 's deteriorated condition. I hope hospice care can help alleviate his pain and gain him some comfort and peace. Our prayers are with you and him. Good luck.
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1 ReactionThank you. On my way for a short visit. I will keep reading this thread and wish all of you good things.
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1 ReactionI saw your comment regarding your friend and looking at pluvicto. My husband just started on this Aug 25 at Duke. In an abundance of caution we are sleeping in different rooms through his treatment. He is having a side effect that’s not listed in trial participants which is a horrid itchy rash that’s been impervious to Benadryl or OTC cortisone cream. Doctors are baffled as it’s not a side effect listed.
This treatment and many other topics were part of the livestream of the Prostate Cancer Research Institute 2022 which happened last weekend. They are on YouTube, at
Many excellent talks occurred over 2 days and I highly recommend them.
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1 ReactionThanks for mentioning the rash. I will be starting Pluvicto in about 3weeks and knew of other possible side effects. At my first nuclear medicine consultation I will be discussing side effects and will bring up the possibility of a rash
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1 ReactionWelcome @ncoic I look forward to your updates on how things go with Pluvicto. What other treatments have you had?
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1 ReactionThank you for this dd2312. This is a long but excellent video filled with Prostate cancer information. I have been looking and listening to it in segments.