Lupron yeah or Lupron nay that is the question.

Posted by dpcarriere @dpcarriere, Feb 13, 2022

I've rationalized my need for Lupron Therapy. But there are holes in my analysis. The holes are there because of lack of data. So I'm in search of data. I want to hear the real data on the pros and cons of Lupron. All I have heard are generalities. Nothing specific, nothing quantatative, so let's get real.
I invite all to participate including moderators as this is relevant to all and also beneficial to all. My initial query. Who, what facility, has my Lupron answers? They have to be there else we would not be using that form of therapy. It had to have been researched into oblivion as are all procedures in the US of A thus justifying their cost structuring. When does Lupron cease to be effective? That is, what quantifiable condition of our tumors renders Lupron useful? If your doctor says you are cured of your cancer then why continue it's use? If it ain't broke why "fix" it??

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

In my PC diagnosed at Mayo MN in 2019.. They immediately gave me the 1st shot of hormone Lupton, (2 months before any radiation) to shrink the cancer "target" .. Making the cancer smaller is a step in the correct direction.. certainly there are side effects but "life" and "science" are good bets.

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@ken82

In my PC diagnosed at Mayo MN in 2019.. They immediately gave me the 1st shot of hormone Lupton, (2 months before any radiation) to shrink the cancer "target" .. Making the cancer smaller is a step in the correct direction.. certainly there are side effects but "life" and "science" are good bets.

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lupron.. is the hormone shot drug.. excuse my spelling..

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@ken82

lupron.. is the hormone shot drug.. excuse my spelling..

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Just out of curiosity here, was the decision made to do radiation before the lupron was administered?

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The treatment was determined to be radiation prior to the shot..

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@ken82

The treatment was determined to be radiation prior to the shot..

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Thanks for that clarification.

I'm trying to figure out, just out of curiosity, why they don't suggest a six month dose right when you get diagnosed while your deciding on a treatment plan with your "team".

For example, my diagnosis (biopsy results) were March, then I waited for an appt with a radiation oncologist to discuss that option then waited for a surgeon to discuss RP, made a decision and scheduled surgery. By the time I got cut 5+ mos had gone by. (2021 so just post COVID max impact on facilities may have extended the normal timeline.)

My invasion was minimal in the nerve and capillary tissues but 6 mos of ADT might have prevented or minimized that. ....or am I missing something altogether...

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@hergiew

I took Lupron for 25 months. Since then my body has almost completely stopped producing testosterone. My testosterone level now wavers between about 10 to 15. I'm very tired. I took a testosterone replacement, AndroGel, for five weeks and my breasts started to develop so I quit taking it. Since then I have not found a way to take testosterone and prevent breast development. Thus, I remain very, very tired with no relief in sight. After taking Lupron for 18 months, I was very tired, especially in my legs, and I expressed the desire to terminate taking it but my urologist insisted I continue for at least another six months. I did but wish I hadn't.

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I know what you’re going through I’m on my second round of Lupron and I hate it also

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@tbmrebel

I know what you’re going through I’m on my second round of Lupron and I hate it also

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Why was Lupron discontinued?
AbbVie would like to inform you that this product has now been discontinued globally across AbbVie due to a lack of demand with newer alternatives available. I'm on Zolodex injections 3 months

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@ken82

The treatment was determined to be radiation prior to the shot..

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I have been on Lupron for 4 years now the first year was difficult with fatigue primarily and hot/cold sweats, but quiet frankly now I feel quite normal. Except I am not as strong and erections are not possible. I did have a bad problem one time after having knee surgery. The opioids they gave me for pain reacted with the Lupron and sent me for a spin. They could not figure it out. I lost 40 lbs in six weeks and was sick as hell. I finally just said the only different was the opioids so I dropped them, dealt with the pain using Tylenol and almost immediately start getting better. Strange the Drs could not find figure it out. I even told them that is what I suspected but they would not listen and put through all these tests which were all normal. Anyway way better now and cancer seems to be stable. Do to anyone on Lupron please be careful with your pain meds if you are given them.

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@hergiew

I took Lupron for 25 months. Since then my body has almost completely stopped producing testosterone. My testosterone level now wavers between about 10 to 15. I'm very tired. I took a testosterone replacement, AndroGel, for five weeks and my breasts started to develop so I quit taking it. Since then I have not found a way to take testosterone and prevent breast development. Thus, I remain very, very tired with no relief in sight. After taking Lupron for 18 months, I was very tired, especially in my legs, and I expressed the desire to terminate taking it but my urologist insisted I continue for at least another six months. I did but wish I hadn't.

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I’ve been on Lupron/Eligard for the past 10 to 11 years. I experienced breast enlargement early in my treatment, and was finally informed by one of my docs that low-dose radiation (three days) of the breast tissue would stop the growth. I did that and sure enough my breasts have not gotten any bigger than they were at that time!

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Also, just a warning to those who may be on Lupron and experiencing a supply problem. Eligard is a readily available option, but it is given subcutaneously and is extremely painful on injection and for an hour or two afterwards. Lupron was never painful at all for me, Mayo Clinic has decided to change their drug of choice to Eligard at least at the Florida clinic. I couldn’ acme I couldn’t tolerate it, so I went the extra mile and opted for a bilateral orchiectomy at 82 years old, wish I had made this decision earlier!

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