I could not tolerate the drugs at all, swelling of hands and feet, dizziness, lethargy, very very sore joints. I was 67. I stopped all drugs after 6 months, and when to a plant based NO OIL diet. I have lost 65 pounds and I walk 2 miles every other day. I have never felt better in my life! I take no supplements, as they also have fillers in them that caused me problems. I only take B12, D thru the winter, and magnesium. Once in a while a calcium if my bones ache. Thats it, thats all. Luck on your new journey. I am 3 years clean after double lumpectomy with radiation.