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@lifetimepain and @imatine. I just wanted to slide in here to add a positive post to stopping Prolia after one year and moving to the once/week dose of Alendronate. I can vouch for the fact that neither the stopping of Prolia nor the beginning of the Alendronate was accompanied by any issues. I simply waited until it was time for the next Prolia injection and substituted it with an oral pill format.

For me the Prolia side effects were exorbitant. If you recall, Prolia is administered as an every six months injection. That puts a lot of medication into your body all at once just to reach the halfway point. My body couldn't handle it. What it does handle well is a weekly pill.

Good luck with finding a positive manner by which to protect your bones.

Chris

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Replies to "@lifetimepain and @imatine. I just wanted to slide in here to add a positive post to..."

I had one shot of Prolia 8 years ago when I was 75. Within a week I had a strange symptom that only a few posters also noted....my sense of taste was weird. One poster described it as "burning mouth". It was especially apparent with coffee. It wasn't the worst side effect, but I said "no more" since it seemed that Prolia wasn't suitable for me. Nothing happened due to stopping; my doctor had me return to Actonal, which I was tolerating just fine. Gradually, my taste started coming back, but still isn't quite normal.
I have noted on this site that last year I was put on Evenity with excellent results and no significant side effects. When my year long dosage was finished, my ENT wanted me to go on Prolia, but I refused, so I'm back to Actonal.