I agree with you about getting tired of taking so many medications.

Have you ever considered going to a pain rehabilitation program like Mayo Clinic offers?
https://www.mayoclinic.org/departments-centers/pain-rehabilitation-center/sections/overview/ovc-20481691
The Mayo Pain Rehabilitation Center concentrates on drug elimination and provides a care team of nurses and doctors to help wean you safely off non medically necessary medications. Their pharmacy researches your medication list then meets with you for consultation and drug education. They help determine what is actually helping you versus not.

The PRC teaches coping skills, self help and self management of symptoms without chemical assistance. Is this an approach you'd be interested in?