PPIs and H2 blockers

Posted by billgil @billgil, Aug 31, 2022

Have been on Pantoprazole for years, stopped working, Doc up my dosage, still not working at night [disrupted sleep, have to take antacids] tried 10 mgs Famotidine before bed, works great.
Anyone else on this regime ? Is it OK to take both ? Is this OK long term ? Thanks Bill

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I've been taking pantoprazole for atleast 10 yrs. Sometimes I had to increase to 2 a day and still it would not work. I've Acid reflux, gerd, hiatal hernia and many other issues all my life. Yes I have had to take Tagament in addition to pantoprazole sometimes. My pharmacist said it was fine. Yes the Tagament worked great, usually with in 15 minutes. I usually stay on a bland diet in order to avoid to taking any additional meds. Most of these types meds are not good for your kidneys.

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Taking Famotidine in addition to the PPI is fine. I had the same problem at night as you describe. The gastroenterologist said that if it works for you, that's perfect. I wonder if they suggest changing the PPI if it "stopped working"? Another possibility is that something changed that caused things to be worse. I think that's what happened to me, after I lifted extremely heavy boxes. See if you have stress or other factors that changed since it stopped working, and address that.

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