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Rising PSA years after radical prostatectomy

Prostate Cancer | Last Active: Mar 5 7:14am | Replies (206)

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@natem

When my psa went from <.1 in 2020, then jumped to .2 in 2021, I was told I had recurrence and I underwent radiation this past Feb-Mar and 6 months Orgyvx. Unfortunately, my psa went to .3 by the time I had my treatment. I believe the Orgyvx brinds psa to undetectable, it did with me. I go back in 5 months for another. I guess that's when I see the result now that I've been off of the adt (Orgyvx).

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Replies to "When my psa went from <.1 in 2020, then jumped to .2 in 2021, I was..."

Not sure if the Orgovyx brings it to undetectable or just helps it. It all seems to be a bit of a crap shoot to me. It may be that the radiation knocks it down and the ADT helps keep it there, and/or (hopefully) starves off the last few stray cells.

My radiation oncologist told me that outcomes are only 3%-5% better with ADT than without. I took it under the "give me all ya got doc" principal. I'm in your shoes as well, but don't really know the docs plan for how long on the orgovyx yet. My guess is that may change depending on how well I'm tolerating it, which is pretty well.

Best of luck to you, hopefully it stays nice and low!