I am trying to taper from Effexor XR 75mg that I have been on for 20+ years. I am trying to do a very slow taper per instructions on the Surviving Antidepressants website. I am down to 73mg after since May 28. That said, yes, I do have stomach issues, mainly nausea and diarrhea, some days. The diarrhea happens when I am feeling anxious (which is most of the time) and the nausea comes when I have tapered too fast.