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Need a ONCO DX test but was started on letrozole before surgery

Breast Cancer | Last Active: Dec 14, 2023 | Replies (33)
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@anjalima

Have you had the surgery? Many oncologists send the surgical tissue for the ONCOTYPE rather than biopsy tissue. This is common.

Edit: upon re reading I see you have had the surgery. I’m not a medical professional but my understanding is that ONCOTYPE can only be done on ER-PR + HER2 negative tumors. Please double check and don’t rely on my research . Your Oncologist should be able to review this with you and tell you if Letrizole was somehow involved . If not move on to another oncologist if possible.

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Replies to "Have you had the surgery? Many oncologists send the surgical tissue for the ONCOTYPE rather than..."
Randy 36 | @randy36 | Aug 22, 2022

Thank you Anjalima for your interest. Apparently, once you start aromatase inhibitors (Letrozole), your tissue samples will no longer work with the test and give a meaningless value. Since I started on letrozole 5 weeks prior to surgery, the only useful tissue available is that of the biopsies. The doctors didn't take into account this issue prior to starting me on it. I didn't know. I'm not angry or looking to point fingers. I am not willing to give up on this until I find reasonable solutions for my health and peace of mind.

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