← Return to Need a ONCO DX test but was started on letrozole before surgery

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@randy36

Thank you. I am not with any major cancer clinic due to my insurance which is the reason I am participating in this site for patient education and support. I have found studies demonstrating promising results by initiating aromatase inhibitors prior to surgery if the time from diagnosis to surgery is extended however there was no mention of preserving options for Onco Type DX testing. Note that I was instructed by my surgeon that the AI's must be held 1 week prior to surgery due toan increase risk of clotting. Onco surgeons and Oncologist may not realize that biopsies generally do not provide adequate tissue, even collectively if more than one for Onco testing. I had four CA+ US-guided and 1+CA stereotactic biopsies at two different facilities (complicating matters more). I'm hoping to catch the attention of someone who may have been in the same bind or a Dr. who can recommend any viable way forward other than facing a future of doubt rather than peace of mind.

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Replies to "Thank you. I am not with any major cancer clinic due to my insurance which is..."

Have you had the surgery? Many oncologists send the surgical tissue for the ONCOTYPE rather than biopsy tissue. This is common.

Edit: upon re reading I see you have had the surgery. I’m not a medical professional but my understanding is that ONCOTYPE can only be done on ER-PR + HER2 negative tumors. Please double check and don’t rely on my research . Your Oncologist should be able to review this with you and tell you if Letrizole was somehow involved . If not move on to another oncologist if possible.