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Are Aromatase Inhibitors prescribed Longer than 10 years?
Breast Cancer | Last Active: Aug 23, 2022 | Replies (13)Comment receiving replies
If you take a look at completed clinical trials that looked into this, you will find that no benefit was statistically significant for staying on AI after 10 years and possibly even for 5. Long term risks are bone mineral loss and elevated cholesterol… the things that are out of our everyday awareness of side effects.
I agree that it feels comforting to be controlling ( limiting) estrogen production when one, such as I , have ER positive diagnosis. I’m just starting month 5 !
Replies to "If you take a look at completed clinical trials that looked into this, you will find..."
I was on a statin for years before my diagnosis and taking D3 oil has kept my vitamin D levels good. My density scans are all good. I asked if I could stop at 4 years - and Oncologist said no since all the studies are based on 5 years. She said taking it for another 5 yrs would only add less than 2% to my chances of reoccurrence. Not worth another 5 years to me - one has to balance life quality as well.
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I was on anastazole for 3 years, then Tamoxifen for 7 years. I didnt have any noticeable negative side effects from the treatment. 6 months after stopping Tamoxifen my cancer had metastasized to my liver and bones. Of course I can't help but wonder what would have happened if I had stayed on the Tamoxifen longer.