Hello @smlofton and welcome to Mayo Clinic Connect. I can tell this has been increasingly frustrating for both your daughter as well as you as her mother. It is great to hear you finally got a colonoscopy ordered for her!

In the meantime, the prep seems to be the next hurdle. I wonder if she has actively included gut health measures into her lifestyle, aside from medications/prescriptions? Some examples include prebiotics and probiotics as well as a high quality liquid collagen. Here is some additional information that you may find helpful.

Prebiotics and Probiotics:
https://www.mayoclinic.org/prebiotics-probiotics-and-your-health/art-20390058
Has gut health supplements and/or gut healthy food like fermented foods been included?