Hi. When I was first diagnosed with Pseudomonas A. I was asked what was my choice for treatment--suppress or eradicate? I felt it would be best to eradicate. The PICC line (after the line was inserted) was basically pain free. Having someone (husband) to make sure I go through the steps each use was helpful. Having to get up in the middle of the night to do the 3rd treatment of the day was somewhat of a challenge but we set the alarm and did it. You just have to keep your eye on the prize. Getting the PICC line is a great way to get antibiotics where needed instead of a pill where it goes to the whole body--especially the gut. I've still had flare ups with Pseudomonas in the 3 years since that experience and now get treated with inhaled Tobramycin. That really gets the gunk out. Not sure there will ever be a complete freedom from having to treat pseu A but we must do what we can to get past the episodes and live life as best as we can. This stuff can beat you down or prove just how strong you are. This site is a wonderful place to go when you have questions or concerns. It's not a club we wanted to become a member of but I thank God for the great wisdom we can connect with. God Bless You. Faye