I started with just Duloxetine and that didn't help much at all. It's hit and miss with Duloxetine and Gabapentin together. Some nights I go to sleep right away with the meds and other nights, I toss and turn because my feet feel hot and swollen. There isn't pain per se, it's more like my feet are bound and they can't get loose. That's a constant. I think it also depends on whether or not I have exercised much during the day. I wear Birkenstocks most of the time and my feet do not hurt at all when I am wearing them. If I take the Birkenstocks off, the feet feel bound. I wear Hokas for exercise and my feet feel okay in them. I've also tried not taking the meds and that has worked for one night but after that one night, I have to start taking the meds again in order to get relief.