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Vitamin K2 and Calcium (CAC) Score

Heart & Blood Health | Last Active: Feb 28, 2023 | Replies (26)
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@lalvo

Hi there.
I'm confused. You say that there have been no clinical trials showing that K supplements can slow calcium deposits on artery walls, but I also read on the NIH site, it says: "In contrast, vitamin K2 is associated with the inhibition of arterial calcification and arterial stiffening. An adequate intake of vitamin K2 has been shown to lower the risk of vascular damage because it activates matrix GLA protein (MGP), which inhibits the deposits of calcium on the walls." Can you clarify the apparent contradiction - I suspect I am missing something.
Thanks.
Leslie

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Replies to "Hi there. I'm confused. You say that there have been no clinical trials showing that K..."
Colleen Young, Connect Director | @colleenyoung | Aug 16, 2022

@lalvo, I noticed that you wished to post a URL to a study with your post. You will be able to add URLs to your posts in a few days. There is a brief period where new members can't post links. We do this to deter spammers and keep the community safe. Clearly the link you wanted to post is not spam. Please allow me to post it for you.
- Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health (2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/

The role of vitamin K, specifically vitamin K2, in heart health is confusing. This more recent article from the American Heart Association referring to 2022 studies helps explain:
- Despite hopes, vitamin K2 supplements fail to slow calcium buildup in heart valve https://www.heart.org/en/news/2022/04/25/despite-hopes-vitamin-k2-supplements-fail-to-slow-calcium-buildup-in-heart-valve

Researchers continue to study the role of vitamin K2, for example:
- Vitamin K Deficiency and Vascular Calcification. Is There Any Evidence about Its Impact on Coronary Artery Disease? https://www.intechopen.com/chapters/77987

It's always best to discuss with your doctor to find out if supplements might be helpful for you and ensure that they are not harmful.

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