I’m 65 yr old diagnosed with osteopenia a year ago, otherwise healthy until I took Reclast. I’ve never had an adverse reaction to any medication so barely paid attention when the dr ran through the possible side effects. Once a year sounded perfect and is for many, however if you have a bad reaction, you can be dealing with it for a long time. Reclast triggered an autoimmune reaction and I’ve been on prednisone for a year, which of courses impairs bone density. I’m getting new scans in a couple of months and will probably need to find an alternative treatment but after this year, I will not do anything that creates such a powerful lode on my system.