So far I had 3 doses of Evenity. I started itching after the first and subsequent infusions. I also had a headache that starts,a couple of days,after the,shots. Some joint pain , fatigue and brain fog as,well that lasts,about a week. I start feeling more like myself after 2,weeks when I have cleared a portion of the drug. The half life is approximately 2weeks, so there is always,some remaining in your system when you get the next dose. I plan to continue as long as I can as long as the side effects don't get worse.