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About to start Prolia: What's your experience?

Osteoporosis & Bone Health | Last Active: Feb 27 10:57am | Replies (126)

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@joan26

Ask your doctor the following:
1. How long (for how many years) can I continue receiving Prolia.
2. At some point will I be required to take a "drug vacation" from Prolia or miss a shot?
3. If the answer to (2) is "yes," what is my risk for fracture while I am off Prolia after being on it for a time?
4. Please tell me about eye issues associated osteoporosis -- specifically macular degeneration -- and the role Prolia might play in this regard.
If your doctor cannot or will not discuss these matters find one who can and will!

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Replies to "Ask your doctor the following: 1. How long (for how many years) can I continue receiving..."

The only way to take a drug holiday from Prolia is to transition off it on a drug from the bisphosphonate family. Stopping Prolia puts you at high risk for spontaneous spinal fractures. The maximum time you can go btwn injections is 7 mos.

I would also ask the doctor about bisphosphonate-related fractures, e.g., longitudinal femur fractures.

Prolia isn't a bisphosponate but is an anti-resorptive drug, like the bisphosohonates, so shares many of the same side effects. Perhaps there is some true 'safe period' for taking the drug without fear of adverse effects? I would want a doctor's answer to that question.