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Ibrance and Letrozole: Newly Diagnosed Treatment

Breast Cancer | Last Active: Jan 22, 2023 | Replies (104)

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@deluga

Unfortunately mine is very negative. I'm 81 is pretty good shape (walking and strength training) but I do have peripheral neuropathy in my legs and was scheduled to start radiation in 2 1/2 weeks. Two weeks ago I started Letrozole (took only 2/3 of a pill) and quit after 3 days. Besides an upflair of my neuropathy which was being perfectly controlled, horrible pain in earlobes of all places, pain in jaw, some joint pain which was bearable, but numbness in neck, which has now spread to lips and checks.

But a friend had no side effects. It's very individual.

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Replies to "Unfortunately mine is very negative. I'm 81 is pretty good shape (walking and strength training) but..."

Deluge, We each have to do what works best for us individually. I have found over the past nine months that my various side effects from Letrozole Have mostly abated. Even though there continues to be some muscle and joint pain, that’s bearable; and seems to respond positively to my walking and strength training.

I do continue to have an occasional bouts of hot flashes. Lol.

My oncologist pointed out that a study has been made where acupuncture has relieved the joint and muscle pains. I have yet to find a acupuncturist anywhere near me that could help in that area.

I have been hypo glycemic (low blood sugar) For as long as I can remember. Now, tests show that my system is going into pre-diabetic mood. My hope is that this side effect, too, will abate overtime.

Some commenters on these threads have had a good experience by trying a different aromatase inhibitor, or different generics or the brand-name of the drug. It's worth trying a few of these alternatives in case they don't yield the same side effects and I hope you consider doing so. You would still have the option of discontinuing the drug but the peace of mind that you didn't leave a possibly viable option untried.