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About to start Prolia: What's your experience?

Osteoporosis & Bone Health | Last Active: Feb 27 10:57am | Replies (126)

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@willow10

I had a meeting with my Dr. the other day and was able to ask some good questions about my treatment going forward after I've finished with Evenity. The fact that I've learned so much and have really put some time into researching different medications is due to the knowledge I've picked up here.
Anyway......my T-score was minus 3.4 on both spine and hip in January. According to her, Evenity is very good at growing hip bones, but less so the spine. Should I get really good results on both, she recommends that I go to Reclast for a year or so, then maybe take a break. Should the spine numbers not improve enough to move me to Ostepoenia land, she would suggest I go on Prolia for a year (it's supposedly very effective for spine density) then go to Reclast. She is careful to transition patients and doesn't just end the Prolia with nothing else in place.
The only cases she has seen of women with atypical fractures were women who had been on Fosamax or the early drugs for over 10 years (and according to her, their doctors just left them there) and she though there had been less than 5 of them. We also talked about osteonecrosis, which she says does occur but is very rare, especially on Evenity. As a matter of fact, if I need deep dental work done, she recommends I do it before I end my Evenity shots.
I've had 5 Evenity shots, and after the first couple have had no side effects other than some injection site pain for a day or two, so

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Replies to "I had a meeting with my Dr. the other day and was able to ask some..."

It's good to read about your plan. I have read that osteonecrosis mostly happens with women who have the larger doses for cancer, and as you said, that the atypical femur fractures occur after several years.

So I met with my doc yesterday. I wanted to post the plan for me. He does give me some choice. I will do Tymlos for 18 months (I have done 9 months). DEXA in 5/23. Then, due to my sensitivity to meds, he will do an infusion of 1mg Reclast (full dose is 5mg). If I don't react I will do the other 4mg in a month or so. He will monitor me via DEXA and thinks I can do just one infusion to "lock the gains in" and take a break. I will do Evenity in the future if needed.

I really had a tough time deciding between Tymlos and Evenity. My hip is -3.9 as I remember but I have 7 spinal fractures. I believed I could do Evenity after Tymlos but not the other way around but doc says insurance may not cover. Hoping for some improvements! Good luck and thanks for the info!
ps I did not know Prolia was so good for spine. I may ask about a year of that after all, or at least discuss that option with Reclast to follow.