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PMR Dosages and Managing Symptoms

Polymyalgia Rheumatica (PMR) | Last Active: Jun 1 1:21pm | Replies (445)

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@jfannarbor

I am not sure how bad 2 mg of prednisone can be. I have been on 2.5 mg for 5 to 10 years. The side effects I see are easy brusing and thin skin which bleeds easily if I get scraped. I have posted on this site two scientific, published medical articles that show that long-term prednisone is not bad. Here is one of the studies that I can easily find: "Low-Dose Prednisone Therapy of the Patient with Early Active Rheumatoid Arthritis: Clinical Efficiency, Disease-Modifying Properties, and Side Effects" A Randomized Double-Blind, Placebo-Controlled Clinical Trial. The other study that I cannot find right now was a Rheumatologist who followed his patients for, I think, 25 years and noted no problems with under 5 mg of prednisone. The complete reference is Ann Intern Med 2002; 136: 1-12

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I found another article about low-dose and long-term prednisone usage. It is in The American Journal of Medicine vol 96 feb 1994 page 115 to 123. It notes no adverse events below 5 mg per day. I still can't find the one published article where a MD followed patients for about 25 years and found a similar result.