I was given Reclast twice. I followed the recommendations of my doctor to take Tylenol and increase fluids, but I had severe flu like symptoms for 4 days afterwards. Fever, fatigue, body aches that put me in bed. My doctor tried it again a year later saying the reaction should be less, but unfortunately it wasn’t. After that she would not give it again. That’s just me. I’m sure others have a more positive experience.