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Has anyone with UC stopped responding to Entyvio?
Digestive Health | Last Active: Jan 26 2:41pm | Replies (48)Comment receiving replies
So sorry to hear what you’re going through but I understand completely! I am also happy to report that the Remicade is working for me!!! I had scheduled a proctocolectomy for last November and my GI doc got approval for me to take the higher dose of Remicade every 4 weeks. My weight was too low, so he had to battle with my insurance company to get authorization for the 500mg infusion every 4 weeks! My calprotectin was 1280 and I was on 60 mg of prednisone daily! So, it has been over 8 months and things are better than they have been in a long time!!! The biologics have different mechanisms of action, so they work differently to reduce the inflammation. Remicade is a TNF inhibitor and has been around a long time. I just had my annual colonoscopy and there has been mucosal healing and improvement!!! So don’t give up!!! There have also been several more drugs (orals) approved in the last 3 months, so for the first time in a long time, I am hopeful!!! Don’t be afraid to try Remicade - it changed my life!!! I wish you the very best!!!! ❤️
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Thank you so much for your reply and understanding! Happy to hear that the Remicade is working for you and that you did not need to go through with the proctocolectomy. It is very helpful to hear that biologics have different mechanisms of action. I questioned whether Remicade would possibly help when the Entyvio was not effective. There does seem to be much progress with the oral meds, however just starting to research this too. Thanks again for your response... I do feel more hopeful and confident in giving the Remicade a try! Wishing you the best too!!