Hello @jamesajohn62 and welcome to Mayo Clinic Connect. Sorry to hear of your complications/additions of health concerns.

I found an existing discussion where members are sharing about neuropathy and sciatica that I thought may be helpful for you to join so you will notice I have moved your post here: https://connect.mayoclinic.org/discussion/peripheral-neruopathy-injections-not-working-tramadol-to-control-pa/

Members such as @pjbaratta @jenatsky @yeoj and @dkappel have shared their experiences in this discussion and am hoping they can come back and support you.

What have you tried to date that hasn't work, as a process of elimination?