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Other causes of failed PEth test for alcohol abuse?
Mental Health | Last Active: Nov 6 9:09pm | Replies (446)Comment receiving replies
Welcome @creigstad,
According to this study "Validation of blood phosphatidylethanol as an alcohol consumption biomarker in patients with chronic liver disease" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409698/, blood transfusion could potentially affect the results of PEth testing.
See this excerpt:
"Large volume blood transfusions could result in false positive or false negative results for PEth testing, as may have been the case for one of our study participants. It is important to note that this was not necessarily a representative sample of patients with liver disease, as recruitment was completed in a regional referral center for liver diseases."
You may wish to discuss with your medical team.
Replies to "Welcome @creigstad, According to this study "Validation of blood phosphatidylethanol as an alcohol consumption biomarker in..."
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Published just days ago:
"Phosphatidylethanol (PEth) is a marker of alcohol consumption used in clinical and forensic settings. PEth positivity in individuals expected to abstain from alcohol can have serious consequences. PEth is located on erythrocytes, thus packed red blood cell (pRBC) transfusion is a potential cause of false-positive results. This report is the first to demonstrate this phenomenon in an authentic patient who was negative for PEth immediately prior to transfusion."