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Has anyone had the PSMA-PET scan? Was cancer found?

Prostate Cancer | Last Active: Feb 4, 2023 | Replies (133)

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@drj

One limitation to broad adoption: the means to generate the radioactive positron-emitting Gallium 68 from its precursor Germanium 68, and likely some subsequent biochemistry. The Gallium 68 isotope has to be generated on site because its half-life is only 68 minutes. I'm uncertain if they use a Cyclotron or other means, and whether there is a purification step, and it must also be mixed with specialized proteins but the bottom line is, it's highly specialized and complicated. At UCLA, they delivered the Gallium 68 - labelled compound from its preparation site somewhere else on campus using a low tech vacuum delivery tube 🙂 all ready to be injected into a vein in my arm, which was already prepped and ported. As a biochemist who has used radioisotopes and antibodies extensively, I can tell you this is frontier stuff. Among the leaders in this: UCLA and UCSF. The technology has also being adapted to TREAT metastases (different isotopes of course) and just been approved in the US. Initial data are understandably small numbers, so we'll see.

You can learn more here (the PSMA/PET of interest starts around 10 minutes in): This is Dr. Reiter at UCLA

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Replies to "One limitation to broad adoption: the means to generate the radioactive positron-emitting Gallium 68 from its..."

Very helpful information. Dr. Thomas Hope's video was especially