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Is there anyone that had estrogen positive cancer, without use of AI?
Breast Cancer | Last Active: Dec 15, 2023 | Replies (146)Comment receiving replies
I started letrozole November one of 2021. At first, I experienced gosh awful hot flashes, hair loss, extremely dry skin, and depression. However, they have pretty much subsided now. My system has always been hypo glycemic (low blood sugar); however I’ve now been diagnosed as prediabetic. The good news is, for me, my last A1c test showed that my system has adjusted back down to just under the prediabetic numbers. My hair seems to have stopped falling out; my skin is becoming more moist. My points: it seems that my body is acclimating to the Letrozole over time and the side effects are calming down for me. My oncologist and I have discussed this. My choice is to hang in there and see where this all goes for me. By the way, I agree with the fact that this 80 year old body had very little estrogen in it to begin with. L O L
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@joiful I have posted before about hormonal meds, both for cancer and for osteoporosis. I think that with meds that affect hormones, side effects change over time. Changes in hormones affect the body but not immediately. I had the same experience: hot flashes and other side effects that faded.
With my osteoporosis meds, also hormonal, this also happened: the fast heart beat and headache faded.
One option with hormonal meds is to start with a lower dose and move up as the body adjusts. For AI's that would mean alternating days, which my docs approved. The Femara insert actually states that 20% of the usual dose is effective.