Thank you for your suggestion. My routine in the morning without changing and getting up earlier, limits me to taking prednisone no earlier than 8am. Dr suggested, late afternoon for second dose. In my opinion, that is going to effect my ability to sleep, as well as the fact that prednisone should be taken with food, which is difficult as I'm active during the afternoon and do not have access or time for eating. I'm interested if splitting doses actually has shown that it benefits/or results in helping reduce prednisone scheduling plans. Goal is to reduce and eliminate prednisone. Thank you.