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@windyshores

Any study of recurrence at 5=10 years is missing the point about rising risk for, say, years 10-15.

All we have is genomic tests at the moment. If they say risk is, like mine, 12% without meds and 6% with meds, and my pathology was relatively scary, I don't think that is far off from the average of 1 in 49. It is more about your chances of being that one!

I think forums tend to the negative and more people who have bad side effects tend to post. So I am glad there is balance in this forum with some, including me, posting more positive experiences.

Protocols change and we need to keep up. Breast Cancer Index is now in the NCCN guidelines. I had the Breast Cancer Index at year 5 of Femara and it told me there was no benefit in continuing meds in years 5-10. Desepite very high ER and PR scores of 95%. Oncotype is used for years 1-5. Many women are continuing meds after 5 years with no benefit. From the site:

"Nearly 95% Of Women With Early-Stage, Hormone Receptor–Positive (HR+) Breast Cancer Do Not Benefit From Extended Endocrine Therapy"

However, my risk was 5.7% for recurrence and was labelled at the time as "high." You can have high risk, no benefit, low risk, positive benefit, high risk, positive benefit and low risk, no benefit.
https://www.breastcancerindex.com/resources-providers?gclid=265aff4aaa6b1c1dac6d9d9e2aff082b&gclsrc=3p.ds&msclkid=265aff4aaa6b1c1dac6d9d9e2aff082b&utm_source=bing&utm_medium=cpc&utm_campaign=Biotheranostics_BCI_HCP&utm_term=Breast%20Cancer%20Index&utm_content=hcp_breast%20cancer

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Replies to "Any study of recurrence at 5=10 years is missing the point about rising risk for, say,..."

I agree 100%… to much negativity around these meds . That’s exactly why I posted that I have been on 9 years and all I had were hot flashes… I hope that gives hope to those women struggling…
In a perfect world I would wish I didn’t need meds … but this world isn’t perfect! For me… hot flashes or sore bones is worth the risk of cancer NOT coming back. My choice, the right choice for me. I know I did all I could…

"Any study of recurrence at 5=10 years is missing the point about rising risk for, say, years 10-15."

In a sense, that's my point. Is the cancer treatment going to become 'drugs for life' at some point? And how many women taking those drugs would have had a recurrence if they'd not taken them? agree we don't know if were among the lucky 48 or are the unlucky 1 in 49.

Hopefully genetic understanding will be the deciding variable, separating those who are clearly at great risk and need a lifetime of proactive preventative treatment and those who are not at such risk. I am very glad that my oncologist suggested doing the testing!