Yes, of course, I went to the doctors and specialists. I was surprised Mayo Clinic would suggest trying ALA and even more suprised that is actually worked. This is a quote from the Mayo website under alternative treatments: "Alpha-lipoic acid. This has been used as a treatment for peripheral neuropathy in Europe for years. Discuss using alpha-lipoic acid with your doctor because it can affect blood sugar levels. Other side effects can include stomach upset and skin rash." I personally never had any side effects at all, and it has been nothing but helpful for several years now. I noticed a difference after a few days and it just got better with time.