Good evening @pamelaz, your report on side effects from Nortriptyline is quite concerning. I have reviewed several lists of side effects and don't see the "stabbing" that you mention even in the occasional list. Overdoses can increase the level of the side effects. So, I am unable to answer your question....." will it go away?".

Sometimes, your pharmacist is the best one to contact about side effects. I have had the same pharmacists, Mike, Rick, and Stacy and they check everything for me. They also may have information about ways to make it go away like the time of day that it is taken and other medications interacting with the Nortriptyline.

How is Tylenol impacting your neuropathy? I will be using Tylenol next week after my bladder surgery so I am wondering. I haven't taken it in years and yet I don't want opioids.

Just a question.....have you used any topicals on your legs, feet, and thighs? There are compounding pharmacies that can use a unique lidocaine-based recipe that your neurologist or other clinician recommends. I used that for quite a while until I found I could replace it with a medical cannabis topical that, for me, relieves me of tingling, numbness, and pain. It is available in two different dosages....one for acute pain and one for chronic pain.

Would you be interested in trying medical cannabis? It has been controlling my neuropathy pain and tingle tangles now for several years.

May you be free of suffering and the causes of suffering.
Chris

Unfortunately the stabbing is a part of the disease. It has ups and downs. Sometimes you get them a lot then you will go weeks without them. The only thing good about them is the pain subsides almost instantly. It’s painful ( unimaginable pain) like being stabbed but it’s like when the knife comes out the pain goes away and there is no residual pain after. But I would be so worried when the next one would come I would tense up. That tensing up made my neuropathy worse.
I hope you can find some comfort. It’s a cruddy disease.