@KLH that sound just like what I am going through! So frustrating because before we started this 2nd trail I was walking an average of 7,000 steps a day, now I can hardly get out the door, I talked to my HF nurse and she ha not gotten back to me but said to take just 1/2 of the lowest dose until she talks to the Dr and that we would probably abandon the Entresto again, my Cardiologist does want me on Spirolactone if we quit the Entresto, Thank you for letting me know I'm not the only one! By the way I have found a grocery delivery service with recipes that are easy & 20 min or less to fix, they are heart healthy & taste good! I also got a robot vacumm that helps keep my floors clean. Keep me up to date with how you are doing.