Cancers vary significantly and two that have similar stage, grading, etc. can have different prognoses and treatment paths. I think that we rely on the art, as well as the science, of medicine when we have good doctors. And reassuring second opinions are always welcome.

I had a Stage 1A cancer that was, in a sense, plain vanilla. A friend had a Stage 0 that required more complicated surgery due to location and closeness to bones. (The surgeon took some bone tissue to biopsy as well.) We both had the OncotypeDX tests and her Oncotype risk of recurrence was 1% lower than mine. Both were low though and we hope they match future reality.