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Aromatase Inhibitors: Did you decide to go on them or not?

Breast Cancer | Last Active: May 12, 2023 | Replies (1190)
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@lisajoann

That was never mentioned to me sadly, I had grade 3 and my ki67 was high so they just said we highly suggest chemo and radiation. I did tamoxifen and now SI. At this point it’s 10 years in and I wish I had it done. I worry every day if it’s coming back… horrible way to live. My concern are my cancer markers… they fluctuate . Scares me.

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Replies to "That was never mentioned to me sadly, I had grade 3 and my ki67 was high..."
windyshores | @windyshores | Jul 3, 2022

@lisajoann I had grade 3 and LVI and ki67% just over the line for high, but a low Oncotype. The Oncotype would still be possible with the specimens from your surgery but would serve no purpose since you have already had chemo, and already made it 10 years. I was told that 30% of grade 3's have low Oncotypes. It would be no different with Oncotype at this point.

I also worry all the time about it coming back but as I said my docs don't do tumor markers. I had a Breast Cancer Index done and a Prosigna Assay, at the 5 year point, using specimens from post-surgery pathology. The Breast Cancer Index showed no benefit from AI in years 5-10 so my only treatment has been mastectomy and 5 years AI. You have done everything possible and I wish you good luck!

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