There are three highly experienced surgeons in NYC for second opinions regarding the Whipple procedure when vasculature is involved. At the Pancreas Center of Columbia Presbyterian Mefical Center is Chief of Surgery of that Department Dr. John Chabot who is noted for doing very difficult and challenging procedures.

At MSKCC is Dr. Michael D’Angelica and others.

NYU Langone Medical Center is Dr. Christopher Wolfgang who was previously at John’s Hopkins.

A study done at Massachusetts General Hospital and published in May 2019 showed that an older drug for treating high blood pressure called Losartan when combined with chemotherapy could be repurposed to shrink tumors away from vasculature. Sixty-one percent of study participants went on to having the Whipple. LetsWinPC.org featured a patient that participated in the study. I personally know of a patient that had this drug regimen that resulted in the tumor being reduced away fro the vasculature and went on to have the Whipple.

Losartan
https://news.harvard.edu/gazette/story/2019/05/mass-general-trial-shows-novel-protocol-improves-pancreatic-cancer-outcomes/