@callalloo, did you have DCIS? Remind me.

@tygerrag2 it is impossible to comment without knowing your pathology results and/or Oncotype score.

I had an Oncotype of 8 and recurrence risk of 6% with meds. I and several of my friends had very little trouble with aromatase inhibitors.

As for bones, I already had osteoporosis before doing my 5 years on letrozole. Bone density went down the first year and stabilized the last 4, or, rather, returned to the normal post-menopausal rate of loss.

I wanted to go on Reclast during treatment but my doc did not want me to due to occasional afib. That risk has since been discounted.

I actually miss my AI. I felt safer while on it!