I have had 8 monthly injections of Evenity. The first injection left me with joint pain and stiffness for about a week. On the recommendation of the Nurse Practitioner I now take Zyrtec an hour before the injection and daiy for a couple of days after the injection. Since starting the Zyrtec I have had no joint pain or stiffness. There is usually soreness at the injection site that lasts about a day. I hope you find relief from your pain.