Hello @pakerbs and welcome to Mayo Clinic Connect. It sounds as though it has bit of a rough transition. I am sorry!

In order to help you best connect with others sharing on this topic, you will notice that I have moved your post into an existing discussion. Members such as @januaryjane, @crittercaregal, and @nattyd77 may be able to come in and share more with you as they are or have taken Motegrity as well.

What side effects besides constipation did you experience after the first day?