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@johnbishop

Hi Ron @ronlud, Welcome to Connect. From my research only the natural form of alpha lipoic acid helps with neuropathy which is why I think the R-ALA costs a little more. Most of the cheaper product brands contain 50% synthetic ALA (S-ALA) and 50% R-ALA). You can find a lot of research papers on the topic of myelin using Google Scholar - https://scholar.google.com/. Probably one of the better sites for details of ALA is Lipoic Acid - Linus Pauling Institute: https://lpi.oregonstate.edu/book/export/html/373

I haven't done much research on dental work and mercury but it might be a question for your doctor or pharmacist. I have quite a few fillings plus an implant and haven't noticed any problems and I've been taking the ALA 600mg of the cheap stuff before starting the protocol in 2016 when I started taking 1200mg of the R-ALA. I do know there are some files on the topic in Solutions to Peripheral Neuropathy Pain & Discomfort Facebook group files (http://facebook.com/groups/spnpd).

Here's a research paper on the topic - hurts my brain to read it 🙂-- White Paper: FDA Update/Review of Potential Adverse Health Risks Associated with Exposure to Mercury in Dental Amalgam: https://www.fda.gov/medical-devices/dental-amalgam-fillings/white-paper-fda-updatereview-potential-adverse-health-risks-associated-exposure-mercury-dental

What type of neuropathy do you have? Can you share a little more about your symptoms and treatments you've tried?

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Replies to "Hi Ron @ronlud, Welcome to Connect. From my research only the natural form of alpha lipoic..."

Thanks John,
Just to make sure I understand your response. You would reccomend the pure r-alpha over the mixed ? As the pure should work better. ( I wish it was less expensive)
Background: I've had the numbness under or maybe I should say thickness in between my toes and balls of my feet for years, but after getting a covid shot, this feeling has started to spread, and sometimes the bottom of my foot feels bruised, like I was hit with a baseball bat on tHe balls of my foot. (That comes and goes) , sometimes a tightness in the tops ofmy feet like a slight sunburn, I also came down with foot drop ( mainly in my big toe, using nmes stimulation for that) ) sent to neurologist , to nerve Dr for the nerve tests in my legs, to mri of spine, to spine Dr, to spine surgeon . And back to neurologist specialist.
Was told I have periphrial neuropathy (mainly because I have diabeties, even though I keep my a1c levels around 6.3. As soon as they see diabeties.. that's the cause, no other discussion about it) and a bulging disk (l5-s1) (and spondilolithisus) compressing nerve root. He wanted to fillet me like a fish, remove the disc and do a fusion. I said, let's try some decompression and pt first. Decompression is working for my back,
I've also been on prednisone for a couple years for pmr.. tapering off of it, down to 6mg. I would like to get ahead of any nerve damage I have so I can walk better ( also have had loss of strength , so I can't walk very far, legs / arms ache ) all kinds of blood work done, low on b6, end e. Started suppliments for those (a b complex so im getting all the b's) along with magnesium glyconate (for muscle twitching) I retired in 2020 and someone flipped a switch on my body and it's decided it's had enough.
I believe I'm taking e erything in the protocol (minus the hemp and r-ala) there may be one or two more . Just don't remember them.

Also, reading the one report it states : It has been suggested that the presence of S-lipoic acid in the racemic mixture may limit the polymerization of R-lipoic acid and enhance its bioavailability. At present, it remains unclear which supplemental form is best to use in clinical trials.
So it may be better to use the mix ?