I was diagnosed with osteoporosis in 2019 and my doctor recommended Prolia treatment. However, before I began the treatment, I was diagnosed with PMR after a Covid shot and placed on prednisone for pain control and reduction of inflammation. The rheumatologist I was seeing for the PMR advised me to go ahead with the Prolia so I received one shot, which did not cause any immediate side effects, but two months later, I experienced severe jaw pain with signs of infection around dental implants that had been in place for twenty years. After removal of the implants, the area failed to heal and a bone was exposed, causing intense pain. I was then diagnosed with ONJ, which was very upsetting since there is no effective treatment or cure for ONJ. Some people heal and others are left with a long term problem. I was very fortunate in this regard, as my jaw eventually healed although only after several months of intense pain. While all of this was going on, I was tapering the prednisone for PMR. I eventually managed to be pain free from both conditions and am now trying decide how to treat the osteoporosis, since doctors recommended against further Prolia or other similar medications.